jueves, 9 de septiembre de 2010

Investigación Original: Apellidos en Gracias a Dios: Estructura Poblacional y Patrones de Residencia en la Moskitia Hondureña Inferidos por el Método de Isonimia

Por: Edwin Francisco Herrera Paz. Universidad Católica de Honduras. Campus San Pedro y San Pablo, San Pedro Sula, Honduras.

Delmy Aracely Mejía de Herrera. Clínica Médica Herrera. San Pedro Sula. Honduras.
Septiembre, 2010
Resumen: El objetivo central de este documento es determinar la estructura genética y las preferencias residenciales de las poblaciones que habitan la Moskitia hondureña, un área amplia de selva lluviosa tropical que comprende el departamento de Gracias a Dios, en la republica de Honduras. Para esto, se calcularon los parámetros corrientes de isonimia dentro y entre los poblados, así como los patrones de residencia utilizando ambos apellidos, a partir del listado de 22,961 electores de 54 localidades agrupadas en seis municipalidades. Se observaron valores altos de isonimia aleatoria y predominancia de patrilocalidad en la mayoría de las comunidades, lo que revela una población estructurada y patrilocal, compuesta principalmente por comunidades aisladas, con la excepción de la ciudad de Puerto Lempira, la cabecera departamental. El análisis de isonimia entre comunidades reveló las rutas migratorias históricas más probables y la relación entre localidades. Los hallazgos sugieren que el departamento de Gracias a Dios es una población estructurada compuesta mayoritariamente por comunidades con alta endogamia y deriva génica, lo que la hace adecuada para la realización de estudios sobre enfermedades de herencia mendeliana y enfermedades complejas. La cabecera departamental, Puerto Lempira, puede ser la única localidad experimentando un rápido proceso de urbanización.
Palabras clave: Apellidos, Isonimia, Genética, Población, Miskitos, Gracias a Dios, Honduras
Summary: The main objective of this paper is to assess the genetic structure and residence preferences of the populations that inhabit the Honduran Moskitia, a wide area of tropical rain forest that comprises the Department of Gracias a Dios, in the republic of Honduras. For this purpose, common isonymy parameters within and between parishes, as well as residence patterns using both surnames were calculated from a list of 22,961 electors at 54 localities, grouped in six municipalities. High random Isonymy values and predominance in patrilocality were observed in most of the communities, revealing a highly structured, patrilocal population composed mainly by relatively isolated communities, with the exception of Puerto Lempira, the capital city. Analysis of isonymy between communities revealed the most probable historical migration routes and relations among locations. The findings suggest that the Department of Gracias a Dios is a structured population composed mostly by communities with high endogamy and genetic drift, which makes it suitable for the performance of genetic studies on mendelian or complex diseases. The capital city of the department, Puerto Lempira, may be the only one experiencing a fast urbanization process.
Key words: Surnames, Isonymy, Genetics, Population, Miskito, Gracias a Dios, Honduras

Artículo completo en inglés aquí: http://www.tsijournals.com/articles/surnames-in-gracias-a-dios-population-structure-and-residencepatterns-in-the-honduran-miskito-territory-assessed-through.pdf

Referencias
1.   Palmer LJ, Cardon LR. (2005) Shaking the tree: mapping complex disease genes with linkage disequilibrium. The Lancet. 366(9492), 1223-1234.
2.   Unoki H, Takahashi A, Kawaguchi T, Hara K, Horikoshi M, Andersen G, Ng DPK, Holmkvist J, Borch-Johnsen K, Jørgensen T, Sandbæk A, Lauritzen T, Hansen T, Nurbaya S, Tsunoda T, Kubo M, Babazono T, Hirose H, Hayashi M, Iwamoto Y, Kashiwagi A, Kaku K, Kawamori R, Shyong Tai E, Pedersen O, Kamatani N, Kadowaki T, Kikkawa R, Nakamura Y, Maeda S. (2008) SNPs in KCNQ1 are associated with susceptibility to type 2 diabetes in East Asian and European populations. Nat Genet. 40(9), 1098-1102.
3.   Rannala B. (2001) Finding genes influencing susceptibility to complex diseases in the post-genome era. Am J Pharmacogenomics.1(3), 203-21.
4.   Vitart V, Carothers AD, Suffolk R. (2005) Increased level of linkage disequilibrium in rural compared to urban communities: a factor to consider in association-study Design. Am J Hum Genet. 76(5), 763-772.
5.   Roberts DF. (1976) Les concepts d’isolats. In: Le´tude des isolats. (ed. Jacqvard A, INED: Paris), pp. 75–92.
6.   Roberts DF. (1980) Genetic structure and the pathology of an isolated population. In: Population structure and genetic disorders. (eds. Eriksson AW, Forsius HR, Nevanlinna HR, Workman PL, Norio RK) Academic Press: New York. pp 7-26.
7.   Leslie PW, McCluer JW, Dyke B. (1981) Genetic implications of mating structure in a Caribbean isolate. Am J Hum Genet. 33(1), 90-104.
8.   Little BB, Malina RM. (2005) Inbreeding avoidance in an isolated indigenous Zapotec community in the valley of Oaxaca, southern Mexico. Hum Biol. 77(3), 305-16.
9.   Fuster V, Colantonio S. (2006) Isonymic analysis of population structure in Gredos, Spain. Coll Antropol. 30(1), 199-203.
10.            Bedoya G, García J, Montoya P, Rojas W, Amézqita ME, Soto I, Lopez MC, Ospina Duque J, Ruiz Linares A. (2006a) Análisis de isonimia entre poblaciones del noroeste de Colombia. Biomédica. 26(4), 538-545.
11.            Bedoya G, Montoya P, García J, Soto I, Bourgeois S, Carvajal L, Labuda D, Alvarez V, Ospina J, Hedrick PW, Ruiz-Linares A. (2006b) Admixture dynamics in Hispanics: a shift in the nuclear genetic ancestry of a South American population isolate. Proc Natl Acad Sci. 103(19), 7234-9.
12.            Rivas RD. (2000) Pueblos Indígenas y Garífuna de Honduras: Una Caracterización. ed. Guaymuras, Tegucigalpa.
13.            Newson L. (2000). El costo de la conquista. 1era Edicion. (ed. Guaymuras, Tegucigalpa), pp. 63-65.
14.            Ibarra E. (2007) La complementariedad cultural en el surgimiento de los grupos Zambos del Cabo de Gracias a Dios, en la Mosquitia, durante los siglos XVII y XVIII. Revista de Estudios Sociales. 26, 105-115. Disponible en Internet en: http://res.uniandes.edu.co/view.php/256/1.php
15.            Conzemius E. (1932) Ethnographical Survey of the Miskito and Sumu Indians of Honduras and Nicaragua. Ed. U.S. Govt. Print. Off: Washington D.C.
16.            Herrera-Paz EF, Matamoros M, Carracedo A. (2010) The Garífuna (Black Carib) people of the Atlantic coasts of Honduras: Population dynamics, structure, and phylogenetic relations inferred from genetic data, migration matrices, and isonymy. Am J Hum Biol. 22(1), 36-44.
17.            Tillman BF. (2004) La influencia Morava en el paisaje de la Mosquitia Honduraña. 1era. Edicion. (ed. Guaymuras, Tegucigalpa) pp. 52-54.
18.            Azofeifa J, Ruiz E, Barrantes R. (1998) Genetic variation and racial admixture in the Miskito of the southern Mosquito Shore, Nicaragua. Rev Biol Trop. 46(1), 157-165.
19.            Matamoros M, Pinto Y, Inda FJ, García O. (2008) Population genetic data for 15 STR loci (Identifiler trademark kit) in Honduras. Leg Med (Tokyo, Japan). 10(5), 281-283.
20.            Herrera-Paz EF, García LF, Aragón-Nieto I, Paredes M. (2008) Allele frequencies distributions for 13 autosomal STR loci in 3 Black Carib (Garífuna) populations of the Honduran Caribbean coasts. Forensic Sci Int Genet. 3(1), e5-e10.
21.            Crow JF, Mange A. (1965) Measurements of inbreeding from the frequency of marriages between persons of the same surnames. Eugen Quart. 12(4), 199–203.
22.            Jorde LB, Morgan K. (1987) Genetic structure of the Utah Mormons: Isonymy analysis. Am J Phys Anthropol. 72(3), 403-412.
23.            Fisher RA. (1943) The relation between the number of species and the number of individuals in a random sample of animal population. J Anim Ecol. 12, 42-58.
24.            Yasuda N, Morton NE. (1967) Studies on human population structure. En: Third International Congress of Human Genetics. (eds. Crow JF, Neel JV), Johns Hopkins Press, Baltimore. pp. 249-265.
25.            Rodriguez-Larralde A, Barrai I, Nesti C, Mamolini E, Scapoli C. (1998) Isonymy and isolation by distance in Germany. Hum Biol. 70(6), 1041-1056.
26.            Barrai I, Rodriguez-Larralde A, Mamolini E, Manni F, Scapoli C. (2001) Isonymy structure of USA population. Am J Phys Anthropol. 114(2), 109–123.
27.            Rodriguez-Larralde A, Scapoli C, Beretta M, Nesti C, Mamolini E, Barrai I. (1998) Isonymy and the genetic structure of Switzerland. II. Isolation by distance. Ann Hum Biol. 25(6), 533–540.
28.            Relethford JH. (1988) Estimate of kinship and genetic distance from surnames. Hum Biol. 60(3), 475-492.
29.            Colantonio SE, Lasker GW, Kaplan BA, Fuster V. (2003) Use of surname models in human population biology: A review of recent developments. Hum Biol. 75(6), 785-807.
30.            Oota H, Settheetham-Ishida W, Tiwawech D, Ishida T, Stoneking M. (2001) Human mtDNA and Y-chromosome variation is correlated with matrilocal versus patrilocal residence. Nat Genet. 29(1), 20-21.
31.            Besaggio D, Fuselli S, Srikummool M, Kampuansai J, Castrì L, Tyler-Smith C, Seielstad M, Kangwanpong D, Bertorelle G. (2007) Genetic variation in Northern Thailand Hill Tribes: origins and relationships with social structure and linguistic differences. BMC Evol Biol. 7(Suppl 2), S12.
32.            Pinto-Cisternas J, Pineda L, Barrai I. (1985) Estimation of inbreeding by isonymy in Iberoamerican populations: an extension of the method of Crow and Mange. Am J Hum Genet. 37(2), 373–385.
33.            Pinto-Cisternas J, Rodriguez-Larralde A, Castro de Guerra D. (1990) Comparison of two Venezuelan populations using the coefficient of relationship by isonymy. Hum Biol. 62(3), 413–419.
34.            Scapoli C, Mamolini E, Carrieri A, Rodriguez-Larralde A, Barrai I. (2007) Surnames in Western Europe: A comparison of the subcontinental populations through isonymy. Theor Popul Biol. 71(1), 37-48.
35.            Sanna E, Iovine MC, Melis M, Floris G. (2006) Lasker’s coefficient of isonymy between and within16 Sardinian villages in the periods 1825–1849, 1875–1899, and 1925–1949. Am J Hum Biol. 18(5), 621-629.
36.            Seielstad M. (2000) Asymmetries in the maternal and paternal genetic histories of Colombian populations. Am J Hum Genet. 67(5), 1062–1066.
37.            Mesa NR, Mondragón MC, Soto ID, Parra MV, Duque C, Ortíz-Barrientos D, García LF, Iván D. Velez ID, Bravo ML, Múnera JG, Bedoya G, Bortolini MC, Ruiz-Linares A. (2000) Autosomal, mtDNA, and Y-chromosome diversity in Amerinds: Pre- and post-Columbian patterns of gene flow in South America. Am J Hum Genet. 67(5), 1277–1286.
38.            Carvajal-Carmona LG, Soto ID, Pineda N, Ortíz-Barrientos D, Duque C, Ospina-Duque J, McCarthy M, Montoya P, Alvarez VM, Bedoya G, Ruiz-Linares A. (2000) Strong Amerind/white sex bias and a possible Sephardic contribution among the founders of a population in northwest Colombia. Am J Hum Genet. 67(5), 1287–1295.
39.            Helms MW. (1970) Matrilocality, social solidarity, and culture contact: three case histories. Southwestern Journal of Anthropology. 26(2), 197-212.
40.            Korotayev A. (2003) Division of Labor by Gender and Postmarital Residence in Cross-Cultural Perspective: A Reconsideration. Cross-Cultural Research. 37(4), 335-372. 
41.            Flores-Fonseca MA. (2005) Migración interna intermunicipal de Honduras. Universidad Nacional Autónoma de Honduras, Instituto de Investigaciones Económicas y Sociales. Tegucigalpa. Documento disponible en internet en: http://poblacion.rds.hn/analisis_investigaciones/Migracion_Intermunicipal_I.pdf
42.            Rudan I, Carothers AD, Polasek O, Hayward C, Vitart V, Biloglav Z, Kolcic I, Zgaga L, Ivankovic D, Vorko-Jovic A, Wilson JF, Weber JL, Hastie N, Wright A, Campbell H. (2008) Quantifying the increase in average human heterozygosity due to urbanization. Eur J Hum Genet. 16(9), 1097-102.
43.            Colantonio SE, Fuster V, Sanz Gimeno A, Reher DS. (2008) Factors related to inbreeding components from isonymy in an urban population: Aranjuez (Spain). J.Biosoc.Sci. 40, 239-246.
44.            Henderson V. (2003) The urbanization process and economic growth: the so-what question. Journal of Economic Growth. 8(1), 47-71.
45.            Antrop M. (2004) Landscape change and urbanization process in Europe. Landscape and Urban Planning. 67(1-4), 9-26.
46.            Flores-Fonseca MA. (2006) Estimaciones de migración rural - urbana. Universidad Nacional Autónoma de Honduras, Instituto de Investigaciones Económicas y Sociales. Tegucigalpa. Documento disponible en internet en: http://poblacion.rds.hn/analisis_investigaciones/investigaciones.html
47.            Rodriguez-Larralde A, Barrai I. (1998) Estudio genético demográfico del Estado Zulia, Venezuela, a través de isonimia. Acta Cient Venez. 49(3), 134-43.
Lea también: Inmigracion-femenina-reciente-en-la comunidad de Bajamar

4 comentarios:

  1. Estoy impresionada... ¡Interesantísimo!
    A. L. Boadla

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  2. Gracias Ana Laura. Sulados hasta la madre patria.

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  3. me interesan la consanguinidad por isonimia, muy clara la explicación del método,y el cruce que hace de las variables
    a.f.sara verazaluce

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  4. Hola Sara, y gracias por tu comentario. ¿Estás trabajando con alguna población específica? Saludos.

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Por favor comente este entrada.